This is to inform that due to some circumstances beyond the organizer control, “2nd Edition of International Conference and Expo on Toxicology and Applied Pharmacology” (Toxicology 2023) Hybrid Event scheduled during June 12-13, 2023 | Rome, Italy has been postponed. The updated dates and venue will be displayed shortly.
Your registration can be transferred to the next edition, if you have already confirmed your participation at the event.
For further details, please contact us at [email protected] or call + 1 (702) 988 2320.
Environmental chemicals are currently regulated almost exclusively on a single-chemical exposure basis. In reality, people are exposed to chemical mixtures on a daily basis via many different exposure scenarios. The global scientific community has supported efforts to develop the [....] » Read More
According to data provided by the European Monitoring Centre for Drugs and Drug Addiction (EMCDDA), more than one quarter of adults (aged 15–64) in the European Union have used an illicit drug at least once in their lifetime. Advances in the sensitivity of analytical techni [....] » Read More
Nitrosamine impurities have been in the center of the stage of impurities in drug products for the past 3 years. Regulators and industry have been deliberating the methods for determining limits for this special class of mutagenic/carcinogenic impurities. Preliminary guidelines h [....] » Read More
Quantum Dots (QDs) are semiconductor nanocrystals that are increasingly used in biology. QDs, especially cadmium based QDs, play an important role in the diagnosis and treatment of cancer due to their intrinsic fluorescence. However, great concerns exist regarding their toxicity [....] » Read More
Quercetin is a plant derived flavonoid that is widely consumed as an antioxidant health supplement. Quercetin has been reported to possess both antioxidant and pro-oxidant effects. Human exposure to Lead (Pb), an inorganic heavy metal pollutant, is well documented and are often a [....] » Read More
A mysterious form of chronic kidney disease (CKD) prevails in epidemic proportions in certain geographical regions of Sri Lanka. A similar clinical entity is world-wide reported. In Sri Lanka, apparently heathy individuals including a substantial proportion of younger people in t [....] » Read More
Mehtylxanthines, the bronchodilators introduced 100 years ago by H.H. Salter for asthma therapy were used as first line of therapy for the obstructive airway disease for five decades. They have now reemerged as important adjuncts in the treatment of bronchial asthma and COPD, how [....] » Read More
With the rapid expansion of the population and the modernization of civilization, environmental contamination from the petroleum refinery sector has surged, necessitating immediate repair.Petroleum pollutinh-degrading bacteria are common in nature and may use these molecules as c [....] » Read More
Arsenic exposure is a major threat to human beings all around the world due to its immense potential to cause various diseases including cancer. In the Southern Assam, arsenic contamination (>10 µg/L) has been reported in the ground water. In addition, population of Sout [....] » Read More
Among non-communicable diseases the cardiovascular disorders are topping the list. Hypercholesterolemia is one of the important risk factors for the genesis of cardiovascular diseases. The cholesterol biosynthesis is attempted to be blocked by various drugs but neither hyperchole [....] » Read More
In the present study, different concentration of potassium dichromate was studied with different pH viz., 6, 7, 8 & 9 in Bold basal medium on alga, Pseudokirchneriella subcapitata. The study met all the validity criteria. Maximum algal biomass of 163 times was recorded in pH [....] » Read More
Plants have been utilized for the cure of different diseases since ancient times. Medicinal importance of the plants is due to presence of phytochemicals having specific physiological action on the human body. A wide variety of activities have been found in these phytochemicals w [....] » Read More
Introduction: CMT1X is an inherited peripheral neuropathy caused by mutations in the GJB-1 gene that encodes for connexin 32 (Cx32). Despite being the second most common form of CMT neuropathies, there are no pharmacologic treatments for CMT1X. We have developed “novologues [....] » Read More
To develop new anti-inflammatory bioactives with improved efficacy and minimal side effects, researchers can learn from ulcerative colitis, an idiopathic inflammation of the colon, which is characterised by inflammation. Ten percent of the world's population is afflicted by u [....] » Read More
Various non-physiological effects ranging from disease to death may occur from direct contact of noxious agents to eyes, skin, and lungs as these agents are utilized globally for crowd dispersal and for women self-defensive purposes. However, defence personal uses such agents in [....] » Read More
Title : Metallothionein as mineral ion carrier agent, reducing agent in metabolism and in toxicology
Bartolome Ribas Ozonas, Royal National Academy of Pharmacy, Spain
Metallothionein is a biomarker in living systems principally for us humans, intracellular reducing agent also in defense for environmental pollution (high levels in mines workers in China have absence of pathology) and for the presence of heavy metals as cadmium, mercury and lead [....] » Read More
Title : Neuroprotective Role of Sodium Butyrate through Suppressing Inflammation and Modulating Antioxidant Enzymes in vitro and High Fat Diet-fed Mice
Al Borhan Bayazid, Konkuk University , Korea, Republic of
The discovery of effective therapeutic agents against neurodegenerative diseases (NDDs) remains challenging. Neurotoxicity, inflammations, and oxidative stress are associating factors of NDDs. Sodium butyrate (NaB) is a short-chain fatty acid found in diet and produced in the gut [....] » Read More
Title : Disease prevention through the promotion of healthy environments, Trachoma: A Public Health Problem
Maria Luisa Mateus, University of Lisbon, Portugal
Trachoma is the leading infectious cause of blindness in the world. Caused by the bacterium Chlamydia trachomatis, recurrent episodes of infection during childhood lead to severe conjunctival inflammation, followed by scarring, and consequent rubbing of the eyelashes on the cor [....] » Read More
Title : Paternal Epigenetic Inheritance: A man’s exposome may impact health of his unborn children and grandchildren
Oskar Karlsson, Stockholm University, Sweden
The continuous exposure to air pollution and the growing number of manmade chemicals is a threat to biota and human health. These exposures can, together with other stressors, cause adverse effects, either alone or via complex interactions. The exposome can be defined as an indiv [....] » Read More
Title : Evaluation of the toxicological effects of the mycotoxin sterigmatocystin on human neuroblastoma SH-SY5Y cells
Veronica Zingales, University of Valencia, Spain
Mycotoxins are low molecular weight toxic secondary metabolites produced by filamentous fungi, mainly belonging to the genera Aspergillus, Fusarium, Alternaria and Penicillium. Currently more than 300 mycotoxins have been identified. Sterigmatocystin (STE) is a mycotoxin produced [....] » Read More
Title : Alteration of Brachionus calyciflorus swimming behavior by cyanopepides: microginin-FR1 and anabaenopeptin-A and microcystin-LR accompanied by decrease of catecholamine activity and degradation of muscle F-actin
Adam Bownik, University of Life Sciences in Lublin, Poland
Certain strains of cyanobacteria, microorganisms forming water blooms produce toxic secondary metabolites. Although various effects of cyanotoxins in aquatic animals are known, little is known on the effects induced by combinations of cyanobacterial oligopeptides and the explaina [....] » Read More
Title : Effects of low dose imidacloprid exposure on pesticide levels and primary DNA damage in blood and brain of male wistar rats
Anja Katic, Institute for Medical Research and Occupational Health, Croatia (Hrvatska)
Imidacloprid is a systemic pesticide used for crop protection and in the veterinary field that belongs to the group of the most widely used insecticides in the world - neonicotinoids. It acts selectively as an agonist on nicotinic acethylcholine receptors in insects. Due to its w [....] » Read More
Title : Biochemical indicators of the effect of tetrahydrocannabinol against cytostatic irinotecan toxicity in a model of mice with syngeneic colon tumor
Suzana Žunec, Institute for Medical Research and Occupational Health, Croatia (Hrvatska)
Irinotecan is one of the most commonly used cytostatics for the treatment of advanced colon cancer. The incidence of this type of cancer is a growing public health problem in all developed countries. Side effects caused by the use of irinotecan significantly reduce the quality of [....] » Read More
Title : Molecular Insights into the Microtubules Depolymerizing Activity of the IL-8 Receptor B Antagonist SB225002
Ahmed E. Goda, Tanta University, Egypt
OBJECTIVE: We have previously reported the novel off-target microtubules destabilizing activity of SB225002, a compound that was originally designed as a selective and potent IL-8 receptor B antagonist. In the present study we investigated the reversibility of SB225002 antimitoti [....] » Read More
Title : Biochemical markers of adaptation of animals to toxic Anthrogenic factors
Arif Mekhtiev, Academician Abdulla Garayev Institute of Physiology, Azerbaijan
Monitoring studies of degree of environmental pollution concern mostly chemical analysis of the pollutants’ levels not taking into account their effects on animals and adaptation potential of the latter to the impact of toxic substances. Our studies were carried out on the [....] » Read More