Speaker at International Conference and Expo on Toxicology and Applied Pharmacology Conference  2022 - Bartolome Ribas Ozonas
Keynote Presentation
Bartolome Ribas Ozonas, Royal National Academy of Pharmacy, Spain

Metallothionein is a biomarker in living systems principally for us humans, intracellular reducing agent also in defense for environmental pollution (high levels in mines workers in China have absence of pathology) and for the presence of heavy metals as cadmium, mercury and lead [....] » Read More

Speaker at International Conference and Expo on Toxicology and Applied Pharmacology Conference  2022 -  Ana Faustino
Keynote Presentation
Ana Faustino , University of Évora, Portugal

N-methyl-N-nitrosourea (MNU) is the oldest member of the nitroso-compounds that can alkylate DNA. It has been used to induce tumor development in several organs, including mammary gland and prostate. The target of MNU depends on the animals’ specie and strain, dose, route, [....] » Read More

Speaker at International Conference and Expo on Toxicology and Applied Pharmacology Conference  2022 - Luis Jesus Villarreal Gomez
Keynote Presentation
Luis Jesus Villarreal Gomez, Autonomous University of Baja California, Mexico

Biocompatibility and cytotoxicity studies are one of the most important features that have to be analysed in samples that are proposed as biomedical devices. Electrospun nanofibers have been gaining much attention in the biomedical industry, because they are interesting tridimens [....] » Read More

Speaker at International Conference and Expo on Toxicology and Applied Pharmacology Conference  2022 - Al Borhan Bayazid
Oral Presentation
Al Borhan Bayazid, Konkuk University , Korea, Republic of

The discovery of effective therapeutic agents against neurodegenerative diseases (NDDs) remains challenging. Neurotoxicity, inflammations, and oxidative stress are associating factors of NDDs. Sodium butyrate (NaB) is a short-chain fatty acid found in diet and produced in the gut [....] » Read More

Speaker at International Conference and Expo on Toxicology and Applied Pharmacology Conference  2022 - Maria Luisa Mateus
Oral Presentation
Maria Luisa Mateus, University of Lisbon, Portugal

Trachoma is the leading infectious cause of blindness in the world. Caused by the bacterium Chlamydia trachomatis, recurrent episodes of infection during childhood lead to severe conjunctival inflammation, followed by scarring, and consequent rubbing of the eyelashes on the cor [....] » Read More

Speaker at International Conference and Expo on Toxicology and Applied Pharmacology Conference  2022 - Oskar Karlsson
Oral Presentation
Oskar Karlsson, Stockholm University, Sweden

The continuous exposure to air pollution and the growing number of manmade chemicals is a threat to biota and human health. These exposures can, together with other stressors, cause adverse effects, either alone or via complex interactions. The exposome can be defined as an indiv [....] » Read More

Speaker at International Conference and Expo on Toxicology and Applied Pharmacology Conference  2022 - Veronica Zingales
Oral Presentation
Veronica Zingales, University of Valencia, Spain

Mycotoxins are low molecular weight toxic secondary metabolites produced by filamentous fungi, mainly belonging to the genera Aspergillus, Fusarium, Alternaria and Penicillium. Currently more than 300 mycotoxins have been identified. Sterigmatocystin (STE) is a mycotoxin produced [....] » Read More

Speaker at International Conference and Expo on Toxicology and Applied Pharmacology Conference  2022 - Adam Bownik
Oral Presentation
Adam Bownik, University of Life Sciences in Lublin, Poland

Certain strains of cyanobacteria, microorganisms forming water blooms produce toxic secondary metabolites. Although various effects of cyanotoxins in aquatic animals are known, little is known on the effects induced by combinations of cyanobacterial oligopeptides and the explaina [....] » Read More

Speaker at International Conference and Expo on Toxicology and Applied Pharmacology Conference  2022 - Brandon Lucke Wold
Oral Presentation
Brandon Lucke Wold , University of Florida, United States

Homeostatic mechanisms for respiratory control are diverse,sophisticated, and redundant, relying on both central and peripheral mechanisms. However, the orchestrated process of breathing under both physiological and pathologic conditions (i.e., stressors and/or illness) [....] » Read More

Speaker at International Conference and Expo on Toxicology and Applied Pharmacology Conference  2022 - Anja Katic
Oral Presentation
Anja Katic, Institute for Medical Research and Occupational Health, Croatia (Hrvatska)

Imidacloprid is a systemic pesticide used for crop protection and in the veterinary field that belongs to the group of the most widely used insecticides in the world - neonicotinoids. It acts selectively as an agonist on nicotinic acethylcholine receptors in insects. Due to its w [....] » Read More

Speaker at International Conference and Expo on Toxicology and Applied Pharmacology Conference  2022 - Suzana Žunec
Oral Presentation
Suzana Žunec, Institute for Medical Research and Occupational Health, Croatia (Hrvatska)

Irinotecan is one of the most commonly used cytostatics for the treatment of advanced colon cancer. The incidence of this type of cancer is a growing public health problem in all developed countries. Side effects caused by the use of irinotecan significantly reduce the quality of [....] » Read More

Speaker at International Conference and Expo on Toxicology and Applied Pharmacology Conference  2022 - Ahmed E. Goda
Oral Presentation
Ahmed E. Goda, Tanta University, Egypt

OBJECTIVE: We have previously reported the novel off-target microtubules destabilizing activity of SB225002, a compound that was originally designed as a selective and potent IL-8 receptor B antagonist. In the present study we investigated the reversibility of SB225002 antimitoti [....] » Read More

Speaker at International Conference and Expo on Toxicology and Applied Pharmacology Conference  2022 - Arif Mekhtiev
Oral Presentation
Arif Mekhtiev, Academician Abdulla Garayev Institute of Physiology, Azerbaijan

Monitoring studies of degree of environmental pollution concern mostly chemical analysis of the pollutants’ levels not taking into account their effects on animals and adaptation potential of the latter to the impact of toxic substances. Our studies were carried out on the [....] » Read More

Speaker at International Conference and Expo on Toxicology and Applied Pharmacology Conference  2022 - Marina Goumenou
Keynote Presentation
Marina Goumenou, University of Crete, Greece

Environmental chemicals are currently regulated almost exclusively on a single-chemical exposure basis. In reality, people are exposed to chemical mixtures on a daily basis via many different exposure scenarios. The global scientific community has supported efforts to develop the [....] » Read More

Speaker at International Conference and Expo on Toxicology and Applied Pharmacology Conference  2022 - Irena Brcic Karaconji
Keynote Presentation
Irena Brcic Karaconji, Institute for Medical Research and Occupational Health, Croatia (Hrvatska)

According to data provided by the European Monitoring Centre for Drugs and Drug Addiction (EMCDDA), more than one quarter of adults (aged 15–64) in the European Union have used an illicit drug at least once in their lifetime. Advances in the sensitivity of analytical techni [....] » Read More

Speaker at International Conference and Expo on Toxicology and Applied Pharmacology Conference  2022 - Raphael Nudelman
Oral Presentation
Raphael Nudelman, Teva Pharmaceuticals, Israel

Nitrosamine impurities have been in the center of the stage of impurities in drug products for the past 3 years. Regulators and industry have been deliberating the methods for determining limits for this special class of mutagenic/carcinogenic impurities. Preliminary guidelines h [....] » Read More

Speaker at International Conference and Expo on Toxicology and Applied Pharmacology Conference  2022 - Mojtaba Panjehpour
Oral Presentation
Mojtaba Panjehpour, Isfahan University of Medical Sciences , Iran (Islamic Republic of)

Quantum Dots (QDs) are semiconductor nanocrystals that are increasingly used in biology. QDs, especially cadmium based QDs, play an important role in the diagnosis and treatment of cancer due to their intrinsic fluorescence. However, great concerns exist regarding their toxicity [....] » Read More

Speaker at International Conference and Expo on Toxicology and Applied Pharmacology Conference  2022 - Francis Uchenna Umeoguaju
Oral Presentation
Francis Uchenna Umeoguaju, University of Port Harcourt, Nigeria

Quercetin is a plant derived flavonoid that is widely consumed as an antioxidant health supplement. Quercetin has been reported to possess both antioxidant and pro-oxidant effects. Human exposure to Lead (Pb), an inorganic heavy metal pollutant, is well documented and are often a [....] » Read More

Speaker at International Conference and Expo on Toxicology and Applied Pharmacology Conference  2022 - Ananda Jayalal
Oral Presentation
Ananda Jayalal, Ministry of Health Sri Lanka, Sri Lanka

A mysterious form of chronic kidney disease (CKD) prevails in epidemic proportions in certain geographical regions of Sri Lanka. A similar clinical entity is world-wide reported. In Sri Lanka, apparently heathy individuals including a substantial proportion of younger people in t [....] » Read More

Speaker at International Conference and Expo on Toxicology and Applied Pharmacology Conference  2022 - Kavita Gulati
Oral Presentation
Kavita Gulati, University of Delhi, India

Mehtylxanthines, the bronchodilators introduced 100 years ago by H.H. Salter for asthma therapy were used as first line of therapy for the obstructive airway disease for five decades. They have now reemerged as important adjuncts in the treatment of bronchial asthma and COPD, how [....] » Read More

Speaker at International Conference and Expo on Toxicology and Applied Pharmacology Conference  2022 - Izharul Haq
Oral Presentation
Izharul Haq, Indian Institute of Technology Guwahati , India

With the rapid expansion of the population and the modernization of civilization, environmental contamination from the petroleum refinery sector has surged, necessitating immediate repair.Petroleum pollutinh-degrading bacteria are common in nature and may use these molecules as c [....] » Read More

Speaker at International Conference and Expo on Toxicology and Applied Pharmacology Conference  2022 - Sweety Nath Barbhuiya
Oral Presentation
Sweety Nath Barbhuiya, Assam University, India

Arsenic exposure is a major threat to human beings all around the world due to its immense potential to cause various diseases including cancer. In the Southern Assam, arsenic contamination (>10 µg/L) has been reported in the ground water. In addition, population of Sout [....] » Read More

Speaker at International Conference and Expo on Toxicology and Applied Pharmacology Conference  2022 - Dibyajyoti Banerjee
Oral Presentation
Dibyajyoti Banerjee, Postgraduate Institute of Medical Education and Research, India

Among non-communicable diseases the cardiovascular disorders are topping the list. Hypercholesterolemia is one of the important risk factors for the genesis of cardiovascular diseases. The cholesterol biosynthesis is attempted to be blocked by various drugs but neither hyperchole [....] » Read More

Speaker at International Conference and Expo on Toxicology and Applied Pharmacology Conference  2022 - Kathirvelu Baskar
Oral Presentation
Kathirvelu Baskar, Department of Ecotoxicology, Ross Lifescience Ltd.- OECD-GLP, India

In the present study, different concentration of potassium dichromate was studied with different pH viz., 6, 7, 8 & 9 in Bold basal medium on alga, Pseudokirchneriella subcapitata. The study met all the validity criteria. Maximum algal biomass of 163 times was recorded in pH [....] » Read More

Speaker at International Conference and Expo on Toxicology and Applied Pharmacology Conference  2022 - Umbreen Rashid
Oral Presentation
Umbreen Rashid, Quaid-i-Azam University, Pakistan

Plants have been utilized for the cure of different diseases since ancient times. Medicinal importance of the plants is due to presence of phytochemicals having specific physiological action on the human body. A wide variety of activities have been found in these phytochemicals w [....] » Read More

Speaker at International Conference and Expo on Toxicology and Applied Pharmacology Conference  2022 - Sukhmanjit Kaur
Poster Presentation
Sukhmanjit Kaur, University of Kansas, United States

Introduction: CMT1X is an inherited peripheral neuropathy caused by mutations in the GJB-1 gene that encodes for connexin 32 (Cx32). Despite being the second most common form of CMT neuropathies, there are no pharmacologic treatments for CMT1X. We have developed “novologues [....] » Read More

Speaker at International Conference and Expo on Toxicology and Applied Pharmacology Conference  2022 - Roshan Kumar
Poster Presentation
Roshan Kumar, Dev Bhoomi institute of Pharmacy , India

To develop new anti-inflammatory bioactives with improved efficacy and minimal side effects, researchers can learn from ulcerative colitis, an idiopathic inflammation of the colon, which is characterised by inflammation. Ten percent of the world's population is afflicted by u [....] » Read More

Speaker at International Conference and Expo on Toxicology and Applied Pharmacology Conference  2022 - Sanghita Das
Poster Presentation
Sanghita Das, Defence Research Laboratory, India

Various non-physiological effects ranging from disease to death may occur from direct contact of noxious agents to eyes, skin, and lungs as these agents are utilized globally for crowd dispersal and for women self-defensive purposes. However, defence personal uses such agents in [....] » Read More

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