Title : Human Serum Albumin and cholesterol: A new thought
Among non-communicable diseases the cardiovascular disorders are topping the list. Hypercholesterolemia is one of the important risk factors for the genesis of cardiovascular diseases. The cholesterol biosynthesis is attempted to be blocked by various drugs but neither hypercholesterolemia or cholesterol associated disorders are getting controlled. So, it seems that our understanding of the regulation of the cholesterol biosynthesis is mostly incomplete. It is in this context we have developed a hypothesis that human serum albumin can regulate cholesterol biosynthesis. In my talk I shall discuss the toxicological and pharmacological aspects of the above concept.